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1

Intracranial IL-17A overexpression decreases cerebral amyloid angiopathy by upregulation of ABCA1 in an animal model of Alzheimer’s disease

Yang, Junling, Kou, Jinghong, Lalonde, Robert, Fukuchi, Ken-ichiro

Journal:

Brain, Behavior, and Immunity

Year:

2017

Language:

english

File:

PDF, 5.58 MB

english, 2017

2

Overproduction of perlecan core protein in cultured cells and transgenic mice

Michael Hart, Ling Li, Tomoyuki Tokunaga, J. Russell Lindsey, John R. Hassell, Alan D. Snow, Ken-ichiro Fukuchi

Journal:

The Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 484 KB

english, 2001

3

Simvastatin enhances learning and memory independent of amyloid load in mice

Ling Li, Dongfeng Cao, Helen Kim, Robin Lester, Ken-ichiro Fukuchi

Journal:

Annals of Neurology

Year:

2006

Language:

english

File:

PDF, 249 KB

english, 2006

4

Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Aβ1-6 upregulates IL-10 expression and reduces amyloid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease

Hong-Duck Kim, Kazuki Tahara, J. Adam Maxwell, Robert Lalonde, Tatsuya Fukuiwa, Kohtaro Fujihashi, Kent R. Van Kampen, Fan-Kun Kong, De-chu C. Tang, Ken-ichiro Fukuchi

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 394 KB

english, 2007

5

Enhancing Th2 immune responses against amyloid protein by a DNA prime-adenovirus boost regimen for Alzheimer's disease

Hong-Duck Kim, Jing-Ji Jin, J. Adam Maxwell, Ken-ichiro Fukuchi

Journal:

Immunology Letters

Year:

2007

Language:

english

File:

PDF, 559 KB

english, 2007

6

Accumulation of amyloid-β protein in exocrine glands of transgenic mice overexpressing a carboxyl terminal portion of amyloid protein precursor

Ken-Ichiro Fukuchi, Ling Li, Michael Hart, J. Russell Lindsey

Journal:

International Journal of Experimental Pathology

Year:

2000

Language:

english

File:

PDF, 389 KB

english, 2000

7

Overexpressions of cDNAs for β-Amyloid Precursor Proteins 695, 751, and 770 Enhance the Secretion of β-Amyloid Precursor Protein Derivatives and the Survival of P19-Derived Neurons

Ken-ichiro Fukuchi, Tauni Ohman, Nocthao Dang, Anetta C. Smith, Clement E. Furlong, George M. Martin

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 528 KB

english, 1996

8

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

Min Song, JingJi Jin, Jeong-Eun Lim, Jinghong Kou, Abhinandan Pattanayak, Jamaal A Rehman, Hong-Duck Kim, Kazuki Tahara, Robert Lalonde, Ken-ichiro Fukuchi

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 790 KB

english, 2011

9

A novel class of unstable 6-thioguanine-resistant cells from dog and human kidneys

Mitchell S. Turker, Raymond J. Monnat, Ken-Ichiro Fukuchi, Patricia A. Johnston, Charles E. Ogburn, Richard E. Weller, James F. Park, George M. Martin

Journal:

Cell Biology and Toxicology

Year:

1988

Language:

english

File:

PDF, 842 KB

english, 1988

10

Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients

Ken-ichiro Fukuchi, Kiyoji Tanaka, Yuichi Kumahara, Kazuo Marumo, Matthew B. Pride, George M. Martin, Raymond J. Monnat

Journal:

Year:

1990

Language:

english

File:

PDF, 478 KB

english, 1990

11

Rapid procedures for prenatal diagnosis of Cockayne syndrome

Kazuhiko Kawai, Mituo Ikenaga, Hideaki Ohtani, Ken-ichiro Fukuchi, Ken-ichi Yamamura, Yuichi Kumahara

Journal:

Journal of Human Genetics

Year:

1983

Language:

english

File:

PDF, 445 KB

english, 1983

12

Neurodegenerative mechanisms in alzheimer disease

Bryce L. Sopher, Ken-Ichiro Fukuchi, Terrance J. Kavanagh, Clement E. Furlong, George M. Martin

Journal:

Molecular and Chemical Neuropathology (Neurochemical Pathology)

Year:

1996

Language:

english

File:

PDF, 1.45 MB

english, 1996

13

Increased Expression of β-Amyloid Protein Precursor and Microtubule-Associated Protein τ During the Differentiation of Murine Embryonal Carcinoma Cells

Ken-ichiro Fukuchi, Samir S. Deeb, Kouzin Kamino, Charles E. Ogburn, Alan D. Snow, Raymond T. Sekiguchi, Thomas N. Wight, Henri Piussan, George M. Martin

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 2.61 MB

english, 1992

14

Neurotoxicity of β-amyloid

Fukuchi, Ken-ichiro, Sopher, Bryce, Martin, George M.

Journal:

Year:

1993

File:

PDF, 153 KB

1993

15

Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism

Kan Liu, Andrew J. Paterson, Fengxue Zhang, Joanne McAndrew, Ken-Ichiro Fukuchi, J. Michael Wyss, Ling Peng, Yong Hu, Jeffrey E. Kudlow

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 553 KB

english, 2004

16

Elevated spontaneous mutation rate in SV40-transformed werner syndrome fibroblast cell lines

Ken-ichiro Fukuchi, Kiyoji Tanaka, Jun Nakura, Yuichi Kumahara, Tsuyoshi Uchida, Yoshio Okada

Journal:

Somatic Cell and Molecular Genetics

Year:

1985

Language:

english

File:

PDF, 470 KB

english, 1985

17

Oxygen-resistant multipotent embryonic carcinoma cell lines exhibit antimutator phenotypes

Charles E. Ogburn, Mitchell S. Turker, Terrance J. Kavanagh, Christine M. Disteche, Annette C. Smith, Ken-ichiro Fukuchi, George M. Martin

Journal:

Somatic Cell and Molecular Genetics

Year:

1994

Language:

english

File:

PDF, 725 KB

english, 1994

18

Activity assays of nine heterogeneous promoters in neural and other cultured cells

Ken-Ichiro Fukuchi, Mark G. Hearn, Samir S. Deeb, Annette C. Smith, Ngocthao Dang, Jun-Ichi Miyazaki, Mark Bothwell, George M. Martin

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1994

Language:

english

File:

PDF, 700 KB

english, 1994

19

Aphidicolin-resistant human cell lines resistant to uv and bleomycin

Kouzin Kamino, Ken-ichiro Fukuchi, Kiyoji Tanaka, Tetsuro Miki, Jun Nakura, Yuji Takemoto, Yuichi Kumahara, Toshio Ogihara

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1993

Language:

english

File:

PDF, 281 KB

english, 1993

20

Trypsin inhibitor activities of fibroblasts increase with age of donor and are unaltered in familial Alzheimer's disease

Mark G. Hearn, Steven D. Edland, Charles E. Ogburn, Annette C. Smith, Thomas D. Bird, George M. Martin, Ken-Ichiro Fukuchi

Journal:

Experimental Gerontology

Year:

1994

Language:

english

File:

PDF, 840 KB

english, 1994

21

Simvastatin enhances immune responses to Aβ vaccination and attenuates vaccination-induced behavioral alterations

Jinghong Kou, Hong-Duck Kim, JingJi Jin, Dongfeng Cao, Ling Li, Robert Lalonde, Ken-ichiro Fukuchi

Journal:

Year:

2010

Language:

english

File:

PDF, 383 KB

english, 2010

22

Combined treatment of Aβ immunization with statin in a mouse model of Alzheimer's disease

Jinghong Kou, Min Song, Abhinandan Pattanayak, Jeong-Eun Lim, Junling Yang, Dongfeng Cao, Ling Li, Ken-ichiro Fukuchi

Journal:

Journal of Neuroimmunology

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

23

Anti-Aβ single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease

Ken-ichiro Fukuchi, Kazuki Tahara, Hong-Duck Kim, J. Adam Maxwell, Terry L. Lewis, Mary Ann Accavitti-Loper, Helen Kim, Selvarangan Ponnazhagan, Robert Lalonde

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 464 KB

english, 2006

24

Overexpression of wild-type and nuclear-targeted catalase modulates resistance to oxidative stress but does not alter spontaneous mutant frequencies at APRT

Samuel E Schriner, Annette C Smith, Ngocthao H Dang, Ken-Ichiro Fukuchi, George M Martin

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2000

Language:

english

File:

PDF, 2.91 MB

english, 2000

25

Reversibility of monocytic differentiation of HL-60 cells by 1α,25 dihydroxyvitamin D3

Shigeru Tomoyasu, Kunihiko Fukuchi, Kazuyuki Watanabe, Hideyuki Ueno, Yasuharu Hamano, Jun-ich Hisatake, Ken-ichiro Hino, Kunihide Gomi, Nobuyoshi Tsuruoka

Journal:

Leukemia Research

Year:

1997

Language:

english

File:

PDF, 837 KB

english, 1997

26

Levels of dna damage are unaltered in mice overexpressing human catalase in nuclei

Samuel E Schriner, Charles E Ogburn, Annette C Smith, Terry G Newcomb, Warren C Ladiges, Martijn E.T Dollé, Jan Vijg, Ken-Ichiro Fukuchi, George M Martin

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 469 KB

english, 2000

27

Overexpression of a C-Terminal Portion of the β-Amyloid Precursor Protein in Mouse Brains by Transplantation of Transformed Neuronal Cells

Ken-ichiro Fukuchi, Dennis D. Kunkel, Philip A. Schwartzkroin, Kouzin Kamino, Charles E. Ogburn, Clement E. Furlong, George M. Martin

Journal:

Experimental Neurology

Year:

1994

File:

PDF, 1.77 MB

1994

28

Homozygosity Mapping of the Werner Syndrome Locus (WRN)

Jun Nakura, Ellen M. Wijsman, Tetsuro Miki, Kouzin Kamino, Chang-En Yu, Junko Oshima, Ken-ichiro Fukuchi, James L. Weber, Charles Piussan, Maria I. Melaragno, Charles J. Epstein, S. Scappaticci, Marco

Journal:

Year:

1994

File:

PDF, 553 KB

1994

29

Narrowing the Position of the Werner Syndrome Locus by Homozygosity Analysis—Extension of Homozygosity Analysis

Jun Nakura, Tetsuro Miki, Lin Ye, Noriaki Mitsuda, Yi Zhao, Koichi Kihara, Chang-En Yu, Junko Oshima, Ken-ichiro Fukuchi, Ellen M. Wijsman, Gerard D. Schellenberg, George M. Martin, Shun-ichi Murano,

Journal:

Year:

1996

Language:

english

File:

PDF, 241 KB

english, 1996

30

Expression of apolipoprotein E inhibits aggregation of the C-terminal fragments of μ-amyloid precursor protein

Tauni Ohman, Nocthao Dang, Renee C. LeBoeuf, Clement E. Furlong, Ken-ichiro Fukuchi

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 633 KB

english, 1996

31

MyD88 Deficiency Ameliorates β-Amyloidosis in an Animal Model of Alzheimer's Disease

Jeong-Eun Lim, Jinghong Kou, Min Song, Abhinandan Pattanayak, Jingji Jin, Robert Lalonde, Ken-ichiro Fukuchi

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

32

The effects of MyD88 deficiency on exploratory activity, anxiety, motor coordination, and spatial learning in C57BL/6 and APPswe/PS1dE9 mice

Jeong-Eun Lim, Min Song, Jingji Jin, Jinghong Kou, Abhinandan Pattanayak, Robert Lalonde, Ken-ichiro Fukuchi

Journal:

Behavioural Brain Research

Year:

2012

Language:

english

File:

PDF, 447 KB

english, 2012

33

Induction of anti-inflammatory immune response by an adenovirus vector encoding 11 tandem repeats of Aβ1–6: Toward safer and effective vaccines against Alzheimer’s disease

Hong-Duck Kim, J. Adam Maxwell, Fan-Kun Kong, De-chu C. Tang, Ken-ichiro Fukuchi

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

34

Amelioration of amyloid load by anti-Aβ single-chain antibody in Alzheimer mouse model

Ken-ichiro Fukuchi, Mary Ann Accavitti-Loper, Hong-Duck Kim, Kazuki Tahara, Yunpeng Cao, Terry L. Lewis, Robert C. Caughey, Helen Kim, Robert Lalonde

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 452 KB

english, 2006

35

Immunization of Alzheimer model mice with adenovirus vectors encoding amyloid β-protein and GM-CSF reduces amyloid load in the brain

Hong-Duck Kim, Fan-Kun Kong, Yunpeng Cao, Terry L. Lewis, Helen Kim, De-chu C. Tang, Ken-ichiro Fukuchi

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 203 KB

english, 2004

36

Lack of LDL receptor aggravates learning deficits and amyloid deposits in Alzheimer transgenic mice

Dongfeng Cao, Ken-ichiro Fukuchi, Hongquan Wan, Helen Kim, Ling Li

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 601 KB

english, 2006

37

Induction of a Th2 immune response by co-administration of recombinant adenovirus vectors encoding amyloid β-protein and GM-CSF

Hong-Duck Kim, Yunpeng Cao, Fan-Kun Kong, Kent R. Van Kampen, Terry L. Lewis, Zhendong Ma, De-chu C. Tang, Ken-Ichiro Fukuchi

Journal:

Year:

2005

Language:

english

File:

PDF, 271 KB

english, 2005

38

Association of Aortic Atherosclerosis with Cerebral β-Amyloidosis and Learning Deficits in a Mouse Model of Alzheimer's Disease

Ling Li, Dongfeng Cao, David W. Garber, Helen Kim, Ken-ichiro Fukuchi

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 731 KB

english, 2003

39

Amyloid-β Deposition in Skeletal Muscle of Transgenic Mice: Possible Model of Inclusion Body Myopathy

Ken-ichiro Fukuchi, Dao Pham, Michael Hart, Ling Li, J. Russell Lindsey

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 767 KB

english, 1998

40

Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity

Ken-ichiro Fukuchi, Kouzin Kamino, Samir S. Deeb, Annette C. Smith, Thao Dang, George M. Martin

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 3.22 MB

english, 1992

41

O4-05-01 Enhancement of learning and memory by statins beyond Alzheimer's disease

Ling Li, Dongfeng Cao, Hongquan Wan, Jianguo Chen, Ken-ichiro Fukuchi, Helen Kim, Robin Lester, Robert Lalonde

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

42

Expression of anti-Aβ single-chain antibody in skeletal muscle reduces Aβ accumulation in an Alzheimer's disease mouse model

Junling Yang, Abhinandan Pattanayak, Min Song, Jinghong Kou, Hiroaki Taguchi, Sudhir Paul, Selvarangan Ponnazhagan, Robert Lalonde, Ken-ichiro Fukuchi

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

43

Muscle-Directed Anti-Aβ Single-Chain Antibody Delivery via AAV1 Reduces Cerebral Aβ Load in an Alzheimer’s Disease Mouse Model

Junling Yang, Abhinandan Pattanayak, Min Song, Jinghong Kou, Hiroaki Taguchi, Sudhir Paul, Selvarangan Ponnazhagan, Robert Lalonde, Ken-ichiro Fukuchi

Journal:

Journal of Molecular Neuroscience

Year:

2013

Language:

english

File:

PDF, 629 KB

english, 2013

44

Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the β-amyloid precursor protein

Bryce L. Sopher, Ken-ichiro Fukuchi, Annette C. Smith, Kathy A. Leppig, Clement E. Furlong, George M. Martin

Journal:

Molecular Brain Research

Year:

1994

Language:

english

File:

PDF, 1.43 MB

english, 1994

45

Transgenic Animal Models for Alzheimer's Disease

KEN-ICHIRO FUKUCHI, CHARLES E. OGBURN, ANNETTE C. SMITH, DENNIS D. KUNKEL, CLEMENT E. FURLONG, SAMIR S. DEEB, DAVID NOCHLIN, S. MARK SUMI, GEORGE M. MARTIN

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 404 KB

english, 1993

46

Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

Jing-Ji Jin, Hong-Duck Kim, J Adam Maxwell, Ling Li, Ken-ichiro Fukuchi

Journal:

Journal of Neuroinflammation

Year:

2008

Language:

english

File:

PDF, 3.36 MB

english, 2008

47

Selective neurotoxicity of COOH-terminal fragments of the β-amyloid precursor protein

Fukuchi, Ken-ichiro, Sopher, Bryce, Furlong, Clement E., Smith, Annette C., Dang, NgocThao, Martin, George M.

Journal:

Neuroscience Letters

Year:

1993

Language:

english

File:

PDF, 421 KB

english, 1993

48

P3-358: Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

Fukuchi, Ken-ichiro, Jin, Jing-Ji, Kim, Hong-Duck, Maxwell, J. Adam, Li, Ling

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 66 KB

english, 2008

49

Expression of a carboxy-terminal region of the β-amyloid precursor protein in a heterogeneous culture of neuroblastoma cells: evidence for altered processing and selective neurotoxicity

Fukuchi, Ken-ichiro, Kamino, Kouzin, Deeb, Samir S., Furlong, Clement E., Sundstrom, Joseph A., Smith, Annette C., Martin, George M.

Journal:

Molecular Brain Research

Year:

1992

Language:

english

File:

PDF, 1.22 MB

english, 1992

50

Beneficial catalytic autoimmunity to beta-amyloid peptide

Nishiyama, Yasuhiro, Planque, Stephanie, Hara, Mariko, Watanabe, Kenji, Xu, Xiaoyun, Taguchi, Hiroaki, Sigurdsson, Einar M., O'Nuallain, Brian, Murray, Ian, Friedland, Robert P., Fukuchi, Ken-ichiro,

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012